Product of personal experience* in dissecting amputated limbs and the understanding of the pathodynamics of the spread of infection in the diabetic foot viz. along the long flexor, intterosseous and lumbical tendons. Pus and gas (in anaerobic infections) accumulates in the mid compartment of the sole between the plantar fascia and the fourth layer causing compression of the plantar vascular arch thus resulting in distal digital ischaemia and gangrene; proximal spread of the infection medially and upwards above the ankle (through the tarsal tunnel) to soleal region causes thrombosis of the subsoleal venous plexus, arterial compression and systemic toxaemia, very often resulting in major amputation of the limb.